The risk factors of keratoconus include:

  • vigorous rubbing of eyes
  • familial history
  • genetic predisposition
  • Down’s syndrome
  • eye allergy and general weakness of connective tissue, but also long-time wearing hard contact lenses.

In majority of cases the disease is hereditary (autosomal dominant hereditary disease, i.e. that 50% of the descendants have the risk of inheriting the disease). The disease affects both men and women with equal frequency, and in 90% of the cases disease process is bilateral.